Question · asked by 1 review

Remdesivir and standard care vs placebo or usual care: All‐cause mortality at up to day 281

Remdesivir and standard care showed no clear difference in all‐cause mortality at up to day 281 compared with standard care (plus/minus placebo) (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Remdesivir and standard care vs standard care (plus/minus placebo)
All‐cause mortality at up to day 281 · hospitalised adults with moderate to severe COVID‐19
Remdesivir and standard care showed no clear difference in all‐cause mortality at up to day 281 compared with standard care (plus/minus placebo) (moderate certainty).
Remdesivir for the treatment of COVID‐19 (2023) · Cochrane Headline outcomes only
RR 0.93 [0.81, 1.06]4 studies · 7142 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Remdesivir for the treatment of COVID‐19
2023 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.