Brivaracetam vs placebo: Withdrawals due to adverse events
Brivaracetam may leads to higher proportion of participants who experienced adverse events leading to… compared with placebo (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Brivaracetam vs placebo Proportion of participants who experienced adverse events leading to treatment withdrawal · people with drug‐resistant focal epilepsy Brivaracetam may leads to higher proportion of participants who experienced adverse events leading to… compared with placebo (low certainty). Brivaracetam add‐on therapy for drug‐resistant epilepsy (2022) · Cochrane Headline outcomes only | RR 1.54 [1.02, 2.33] | 6 studies · 2411 participants | Low |
Brivaracetam vs placebo Proportion of participants who experienced adverse events leading to treatment withdrawal · patients with drug‐resistant focal epilepsy Brivaracetam may leads to higher proportion of participants who experienced adverse events leading to… compared with placebo (low certainty). Brivaracetam add‐on therapy for drug‐resistant epilepsy (2019) · Cochrane Headline outcomes onlyearlier version CD011501.PUB2, superseded | RR 1.54 [1.02, 2.33] | 6 studies · 2411 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Brivaracetam add‐on therapy for drug‐resistant epilepsy 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.