Question · asked by 1 review

Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics vs Matched placebo, partial or total chemo-mechanical debridement and analgesics: Percussion pain at 72 hours

Population
Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or systemic involvement)
Intervention
Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics
Comparison
Matched placebo, partial or total chemo-mechanical debridement and analgesics
Outcome
Percussion pain at 72 hours

Postoperative systemic antibiotics… showed no clear difference in percussion pain at 72 hours compared with matched placebo, partial or total chemo-mechanical debridement and…; GRADE not reported.

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics vs Matched placebo, partial or total chemo-mechanical debridement and analgesics
Percussion pain at 72 hours · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or… · 72 hours
Postoperative systemic antibiotics… showed no clear difference in percussion pain at 72 hours compared with matched placebo, partial or total chemo-mechanical debridement and…; GRADE not reported.
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults (2024) · Cochrane All outcomes
MD 0.05 [-0.55, 0.65]1 study · 41 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults
2024 · Cochrane All outcomes
2022-11Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.