Question · asked by 1 review

Exposure to gonadotropins for subfertility vs general population and endometrial cancer risk: Endometrial cancer

It is very uncertain whether exposure to gonadotropins for subfertility changes endometrial cancer compared with general population and endometrial cancer risk (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Exposure to gonadotropins for subfertility vs general population and endometrial cancer risk
Endometrial cancer · Women treated with ovary‐stimulating drugs for subfertility
It is very uncertain whether exposure to gonadotropins for subfertility changes endometrial cancer compared with general population and endometrial cancer risk (very low certainty).
Risk of endometrial cancer in women treated with ovary‐stimulating drugs for subfertility (2017) · Cochrane Headline outcomes only
RR 2.12 [0.79, 5.64]2 studies · 1595 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Risk of endometrial cancer in women treated with ovary‐stimulating drugs for subfertility
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.