Question · asked by 1 review

Chlorhexidine mouthrinse (any concentration; 0.05% to 0.2%) used in conjunction with mechanical oral hygiene procedures vs Placebo/control mouthrinse, or no mouthrinse (mechanical oral hygiene alone); controls pooled (protocol's separate comparisons versus mechanical oral hygiene alone and versus placebo/control merged): Extrinsic tooth staining (various staining indices)

Population
Children or adults with gingivitis or periodontitis capable of performing normal mechanical oral hygiene procedures (some with medical conditions or special care needs)
Intervention
Chlorhexidine mouthrinse (any concentration; 0.05% to 0.2%) used in conjunction with mechanical oral hygiene procedures
Comparison
Placebo/control mouthrinse, or no mouthrinse (mechanical oral hygiene alone); controls pooled (protocol's separate comparisons versus mechanical oral hygiene alone and versus placebo/control merged)
Outcome
Extrinsic tooth staining (various staining indices)

Chlorhexidine mouthrinse (any concentration; 0.05% to 0.2%) used in… led to higher extrinsic tooth staining (various staining indices) compared with placebo/control mouthrinse, or no mouthrinse (mechanical oral…; GRADE not reported.

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 1 · 50%Very low 0 · 0%Low 0 · 0%Moderate 1 · 50%High 0 · 0%
FindingEffectStudiesGRADE certainty
Chlorhexidine mouthrinse (any concentration; 0.05% to 0.2%) used in conjunction with mechanical oral hygiene procedures vs Placebo/control mouthrinse, or no mouthrinse (mechanical oral hygiene alone); controls pooled (protocol's separate comparisons versus mechanical oral hygiene alone and versus placebo/control merged)
Extrinsic tooth staining (various staining indices) · Children or adults with gingivitis or periodontitis capable of performing normal mechanical oral hygiene procedures… · 6 months
Chlorhexidine mouthrinse (any concentration; 0.05% to 0.2%) used in… led to higher extrinsic tooth staining (various staining indices) compared with placebo/control mouthrinse, or no mouthrinse (mechanical oral…; GRADE not reported.
Chlorhexidine mouthrinse as an adjunctive treatment for gingival health (2017) · Cochrane All outcomes
SMD 1.54 [1.22, 1.86]4 studies · 323 participantsGRADE not reported
Chlorhexidine mouthrinse (any concentration; 0.05% to 0.2%) used in conjunction with mechanical oral hygiene procedures vs Placebo/control mouthrinse, or no mouthrinse (mechanical oral hygiene alone); controls pooled (protocol's separate comparisons versus mechanical oral hygiene alone and versus placebo/control merged)
Extrinsic tooth staining (various staining indices) · Children or adults with gingivitis or periodontitis capable of performing normal mechanical oral hygiene procedures… · 4 to 6 weeks
Chlorhexidine mouthrinse (any concentration; 0.05% to 0.2%) used in… probably leads to higher extrinsic tooth staining (various staining indices) compared with placebo/control mouthrinse, or no mouthrinse (mechanical oral… (moderate certainty).
Chlorhexidine mouthrinse as an adjunctive treatment for gingival health (2017) · Cochrane All outcomes
SMD 1.07 [0.80, 1.34]8 studies · 415 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Chlorhexidine mouthrinse as an adjunctive treatment for gingival health
2017 · Cochrane All outcomes
2016-09Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.