Question · asked by 1 review

Long‐term red cell transfusion vs usual care: All‐cause mortality

Population
prevention of SCI in people with SCD and normal TCD velocities
Intervention
Long‐term red cell transfusion
Comparison
usual care
Outcome
All‐cause mortality

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Long‐term RBC transfusion vs standard care
All‐cause mortality · prevention of SCI in people with SCD and normal TCD velocities
Interventions for preventing silent cerebral infarcts in people with sickle cell disease (2020) · Cochrane Headline outcomes only
no estimate extracted1 study · 196 participantsLow
Long‐term RBC transfusion vs standard care
All‐cause mortality · prevention of SCI in people with SCD and normal TCD velocities
Interventions for preventing silent cerebral infarcts in people with sickle cell disease (2017) · Cochrane Headline outcomes onlyearlier version CD012389.PUB2, superseded
no estimate extracted1 study · 196 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for preventing silent cerebral infarcts in people with sickle cell disease
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.