Paroxetine vs hypericum: Failure to respond at endpoint (6‐12 weeks)
Paroxetine showed no clear difference in failure to respond at endpoint (6‐12 weeks) compared with hypericum (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Paroxetine vs hypericum Failure to respond at endpoint (6‐12 weeks) · patients with depression Paroxetine showed no clear difference in failure to respond at endpoint (6‐12 weeks) compared with hypericum (moderate certainty). Paroxetine versus other anti‐depressive agents for depression (2014) · Cochrane Headline outcomes only | OR 1.6 [0.95, 2.69] | 1 study · 251 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.