Question · asked by 1 review

Elective neck dissection (at time of primary tumour resection) vs Therapeutic (delayed) neck dissection: Adverse events associated with treatment

Population
Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
Intervention
Elective neck dissection (at time of primary tumour resection)
Comparison
Therapeutic (delayed) neck dissection
Outcome
Adverse events associated with treatment

Elective neck dissection (at time of primary tumour resection) probably leads to higher adverse events associated with treatment compared with therapeutic (delayed) neck dissection (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Elective neck dissection (at time of primary tumour resection) vs Therapeutic (delayed) neck dissection
Adverse events associated with treatment · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
Elective neck dissection (at time of primary tumour resection) probably leads to higher adverse events associated with treatment compared with therapeutic (delayed) neck dissection (moderate certainty).
Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment (2023) · Cochrane All outcomes
RR 1.31 [1.11, 1.54]2 studies · 746 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment
2023 · Cochrane All outcomes
2022-02Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.