Co-presence of Veillonella spp. with Streptococcus mutans vs Streptococcus mutans acidogenesis without Veillonella spp. modulation (conceptual): Streptococcus mutans acid (lactic acid) production and cariogenic potential
The review concludes that Veillonella spp. may modulate (often inhibit) S. mutans acid production and compete for lactate substrate, potentially reducing cariogenesis, but the evidence is narrative and ungraded.
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Co-presence of Veillonella spp. with Streptococcus mutans vs Streptococcus mutans acidogenesis without Veillonella spp. modulation (conceptual) Streptococcus mutans acid (lactic acid) production and cariogenic potential · Oral biofilm of children/individuals at risk of dental caries · Community and clinical pediatric dental settings (USA, Hong Kong, Indonesia); saliva or dental plaque microbial sampling The review concludes that Veillonella spp. may modulate (often inhibit) S. mutans acid production and compete for lactate substrate, potentially reducing cariogenesis, but the evidence is narrative and ungraded. A systematic review of Streptococcus Mutans and Veillonellae species interactions in dental caries… (2025) All outcomes | Narrative synthesis (no effect estimate): Veillonella spp. can inhibit acid production by S. mutans and compete for substrate by utilizing lactic acid, a by-product of S. mutans metabolism, as a carbon source,… | Not reported | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| A systematic review of Streptococcus Mutans and Veillonellae species interactions in dental caries progression: Positive or Negative impact? 2024 All outcomes | 18 July 2023 (databases searched from inception) | 7 | Not applicable |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.