Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation: Global state ‐ number of participants with relapse/exacerbations of psychosis (combined time points)
Summary of findings table ‐ Antipsychotic dose reduction may leads to higher global state ‐ number of participants with relapse/exacerbations of… compared with dose continuation (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation Global state ‐ number of participants with relapse/exacerbations of psychosis (combined time points) · people with schizophrenia Summary of findings table ‐ Antipsychotic dose reduction may leads to higher global state ‐ number of participants with relapse/exacerbations of… compared with dose continuation (low certainty). Antipsychotic dose reduction compared to dose continuation for people with schizophrenia (2022) · Cochrane Headline outcomes only | RR 2.16 [1.52, 3.06] | 20 studies · 2481 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antipsychotic dose reduction compared to dose continuation for people with schizophrenia 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.