Levamisole vs steroids or placebo or both, or no treatment: Relapse during treatment (4 to 12 months)
Levamisole may leads to lower relapse during treatment (4 to 12 months): includingWeiss 1993 compared with steroids or placebo or both, or no treatment (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Levamisole vs steroids or placebo or both, or no treatment Relapse during treatment (4 to 12 months): includingWeiss 1993 · children with steroid‐sensitive nephrotic syndrome Levamisole may leads to lower relapse during treatment (4 to 12 months): includingWeiss 1993 compared with steroids or placebo or both, or no treatment (low certainty). Non‐corticosteroid immunosuppressive medications for steroid‐sensitive nephrotic syndrome in children (2013) · Cochrane Headline outcomes onlyearlier version CD002290.PUB4, superseded | RR 0.47 [0.24, 0.89] | 7 studies · 375 participants | Low |
Levamisole vs steroids or placebo or both, or no treatment Relapse during treatment (4 to 12 months): excludingWeiss 1993 · children with steroid‐sensitive nephrotic syndrome Levamisole may leads to lower relapse during treatment (4 to 12 months): excludingWeiss 1993 compared with steroids or placebo or both, or no treatment (low certainty). Non‐corticosteroid immunosuppressive medications for steroid‐sensitive nephrotic syndrome in children (2013) · Cochrane Headline outcomes onlyearlier version CD002290.PUB4, superseded | RR 0.41 [0.27, 0.61] | 6 studies · 327 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Non‐corticosteroid immunosuppressive medications for steroid‐sensitive nephrotic syndrome in children 2020 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.