Question · asked by 1 review

RISPERIDONE DEPOT vs QUETIAPINE: Adverse events: Movement disorder ‐ any extra pyramidal symptom

Population
patients with schizophrenia
Intervention
RISPERIDONE DEPOT
Comparison
QUETIAPINE
Outcome
Adverse events: Movement disorder ‐ any extra pyramidal symptom

RISPERIDONE DEPOT may leads to higher adverse events: Movement disorder ‐ any extra pyramidal symptom compared with ORAL QUETIAPINE (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
RISPERIDONE DEPOT vs ORAL QUETIAPINE
Adverse events: Movement disorder ‐ any extra pyramidal symptom · patients with schizophrenia
RISPERIDONE DEPOT may leads to higher adverse events: Movement disorder ‐ any extra pyramidal symptom compared with ORAL QUETIAPINE (low certainty).
Risperidone (depot) for schizophrenia (2016) · Cochrane Headline outcomes only
RR 1.83 [1.07, 3.15]1 study · 666 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Risperidone (depot) for schizophrenia
2016 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.