Question · asked by 1 review

Gabapentin vs placebo: Nausea

Gabapentin probably leads to lower adverse effects: nauseaNumber of participants experiencing nausea compared with placebo (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Gabapentin vs placebo
Adverse effects: nauseaNumber of participants experiencing nausea · people with drug‐resistant focal epilepsy
Gabapentin probably leads to lower adverse effects: nauseaNumber of participants experiencing nausea compared with placebo (moderate certainty).
Gabapentin add‐on treatment for drug‐resistant focal epilepsy (2021) · Cochrane Headline outcomes only
RR 0.954 studies · 1034 participantsModerate
Gabapentin vs placebo
Adverse effects: nausea Number of participants experiencing nausea · people with drug‐resistant focal epilepsy
Gabapentin probably leads to lower adverse effects: nausea Number of participants experiencing nausea compared with placebo (moderate certainty).
Gabapentin add‐on treatment for drug‐resistant focal epilepsy (2018) · Cochrane Headline outcomes onlyearlier version CD001415.PUB3, superseded
RR 0.954 studies · 1034 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Gabapentin add‐on treatment for drug‐resistant focal epilepsy
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.