Question · asked by 1 review

Nicotine EC vs non‐nicotine EC: Adverse events at 1 week to 6 months Assessed via self‐report

Nicotine EC showed no clear difference in adverse events at 1 week to 6 months Assessed via self‐report compared with non‐nicotine EC (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Nicotine EC vs non‐nicotine EC
Adverse events at 1 week to 6 months Assessed via self‐report · People who smoke cigarettes
Nicotine EC showed no clear difference in adverse events at 1 week to 6 months Assessed via self‐report compared with non‐nicotine EC (moderate certainty).
Electronic cigarettes for smoking cessation (2024) · Cochrane Headline outcomes only
RR 1.01 [0.91, 1.11]5 studies · 840 participantsModerate
Nicotine EC vs non‐nicotine EC
Adverse events at 1 week to 6 months Assessed via self‐report · People who smoke cigarettes
Nicotine EC showed no clear difference in adverse events at 1 week to 6 months Assessed via self‐report compared with non‐nicotine EC (moderate certainty).
Electronic cigarettes for smoking cessation (2022) · Cochrane Headline outcomes onlyearlier version CD010216.PUB7, superseded
RR 1.01 [0.91, 1.11]5 studies · 840 participantsModerate
Nicotine EC vs non‐nicotine EC
Adverse events at 1 week to 6 months Assessed via self‐report · People who smoke cigarettes
Nicotine EC showed no clear difference in adverse events at 1 week to 6 months Assessed via self‐report compared with non‐nicotine EC (moderate certainty).
Electronic cigarettes for smoking cessation (2021) · Cochrane Headline outcomes onlyearlier version CD010216.PUB5, superseded
RR 1.01 [0.91, 1.11]3 studies · 601 participantsModerate
Nicotine EC vs non‐nicotine EC
Adverse events at 1 week to 6 months Assessed via self‐report · People who smoke cigarettes
Nicotine EC showed no clear difference in adverse events at 1 week to 6 months Assessed via self‐report compared with non‐nicotine EC (moderate certainty).
Electronic cigarettes for smoking cessation (2021) · Cochrane Headline outcomes onlyearlier version CD010216.PUB6, superseded
RR 1.01 [0.91, 1.11]3 studies · 601 participantsModerate
Nicotine EC vs non‐nicotine EC
Adverse events at 1 week to 6 months Assessed via self‐report · People who smoke cigarettes
Nicotine EC showed no clear difference in adverse events at 1 week to 6 months Assessed via self‐report compared with non‐nicotine EC (low certainty).
Electronic cigarettes for smoking cessation (2020) · Cochrane Headline outcomes onlyearlier version CD010216.PUB4, superseded
RR 1 [0.73, 1.36]2 studies · 346 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Electronic cigarettes for smoking cessation
2024 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.