CPP-ACP vs Pre-treatment (baseline, same group): Quantitative light-induced fluorescence (QLF), fluorescence loss
Compared with baseline, CPP-ACP significantly improved white spot lesions on QLF (SMD -0.43, 95% CI -0.79 to -0.07; ungraded).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
CPP-ACP paste (casein phosphopeptide-amorphous calcium phosphate) vs Baseline (same subjects, pre-treatment) Quantitative light-induced fluorescence (QLF), fluorescence loss · Patients with white spot lesions (children/adolescents) · 4 weeks to 1 year, Clinical (patients with white spot lesions), CPP-ACP vs baseline Compared with baseline, CPP-ACP significantly improved white spot lesions on QLF (SMD -0.43, 95% CI -0.79 to -0.07; ungraded). Evaluation of the efficacy of casein phosphopeptide-amorphous calcium phosphate on remineralization of white… (2019) All outcomes | SMD -0.43 [-0.79, -0.07] | 2 studies · 62 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Evaluation of the efficacy of casein phosphopeptide-amorphous calcium phosphate on remineralization of white spot lesions in vitro and… 2019 All outcomes | May 20, 2019 | 12 | Critically Low / Critically Low |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.