Question · asked by 1 review

Clobetasol-17-propionate 0.025% lipid-loaded microspheres vs Clobetasol propionate 0.025% ointment: Physician Global Assessment (Thongprasom score)

Population
People with erosive oral lichen planus
Intervention
Clobetasol-17-propionate 0.025% lipid-loaded microspheres
Comparison
Clobetasol propionate 0.025% ointment
Outcome
Physician Global Assessment (Thongprasom score)

Clobetasol-17-propionate 0.025% lipid-loaded microspheres showed no clear difference in physician Global Assessment (Thongprasom score) compared with conventional 0.025% clobetasol lipophilic ointment in hydrophilic…; GRADE not reported.

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Clobetasol-17-propionate 0.025% lipid-loaded microspheres vs Conventional 0.025% clobetasol lipophilic ointment in hydrophilic phase
Physician Global Assessment (Thongprasom score) · People with erosive oral lichen planus
Clobetasol-17-propionate 0.025% lipid-loaded microspheres showed no clear difference in physician Global Assessment (Thongprasom score) compared with conventional 0.025% clobetasol lipophilic ointment in hydrophilic…; GRADE not reported.
Interventions for erosive lichen planus affecting mucosal sites (2012) · Cochrane All outcomes
MD 0.00 [-0.61, 0.61]1 study · 45 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for erosive lichen planus affecting mucosal sites
2012 · Cochrane All outcomes
2009-09Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.