Question · asked by 1 review

Mifepristone (all doses) vs placebo: Side effects ‐ amenorrhoea

Mifepristone leads to higher side effects: amenorrhoea compared with placebo (high certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Mifepristone vs placebo
Side effects: amenorrhoea · women with symptomatic endometriosis
Mifepristone leads to higher side effects: amenorrhoea compared with placebo (high certainty).
Progesterone receptor modulators for endometriosis (2017) · Cochrane Headline outcomes only
OR 686.16 [92.29, 5101.33]1 study · 360 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Progesterone receptor modulators for endometriosis
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.