Question · asked by 1 review

Discontinuation by "tapering" vs usual family planning care: Adverse events

It is very uncertain whether discontinuation by "tapering" changes adverse events compared with continuation (or usual care) (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Discontinuation by "tapering" vs continuation (or usual care)
Adverse events · participants with depressive or anxiety disorders
It is very uncertain whether discontinuation by "tapering" changes adverse events compared with continuation (or usual care) (very low certainty).
Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and… (2021) · Cochrane Headline outcomes only
OR 1.06 [0.82, 1.38]7 studies · 1479 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety disorders in adults
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.