Question · asked by 1 review

Azithromycin vs vitamin C: Proportion of participants achieving PASI 75 or PGA 1 to 2

Population
people with chronic plaque psoriasis
Intervention
Azithromycin
Comparison
vitamin C
Outcome
Proportion of participants achieving PASI 75 or PGA 1 to 2

It is very uncertain whether azithromycin changes proportion of participants achieving PASI 75 or PGA 1 to 2 compared with vitamin C (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Azithromycin vs vitamin C
Proportion of participants achieving PASI 75 or PGA 1 to 2 · chronic plaque psoriasis
It is very uncertain whether azithromycin changes proportion of participants achieving PASI 75 or PGA 1 to 2 compared with vitamin C (very low certainty).
Antistreptococcal interventions for guttate and chronic plaque psoriasis (2019) · Cochrane Headline outcomes only
RR 25.06 [1.6, 393.59]1 study · 50 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antistreptococcal interventions for guttate and chronic plaque psoriasis
2019 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.