Question · asked by 1 review

Perioperative beta‐blockers vs placebo or usual care: Ventricular arrhythmias (within 30 days)

Population
adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk surgeries)
Intervention
Perioperative beta‐blockers
Comparison
placebo or usual care
Outcome
Ventricular arrhythmias (within 30 days)

It is very uncertain whether perioperative beta‐blockers changes ventricular arrhythmias (within 30 days) compared with placebo or standard care (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Perioperative beta‐blockers vs placebo or standard care
Ventricular arrhythmias (within 30 days) · adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk…
It is very uncertain whether perioperative beta‐blockers changes ventricular arrhythmias (within 30 days) compared with placebo or standard care (very low certainty).
Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing… (2019) · Cochrane Headline outcomes only
RR 0.72 [0.35, 1.47]5 studies · 476 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing non‐cardiac surgery
2019 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.