Question · asked by 1 review

RISPERIDONE DEPOT vs GENERAL ORAL ANTIPSYCHOTICS: Adverse events: Specific ‐ prolactin‐related ‐ long term It is unclear how adverse events were reported

Population
patients with schizophrenia
Intervention
RISPERIDONE DEPOT
Comparison
GENERAL ORAL ANTIPSYCHOTICS
Outcome
Adverse events: Specific ‐ prolactin‐related ‐ long term It is unclear how adverse events were reported

It is very uncertain whether RISPERIDONE DEPOT changes adverse events: Specific ‐ prolactin‐related ‐ long term It is… compared with GENERAL ORAL ANTIPSYCHOTICS (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
RISPERIDONE DEPOT vs GENERAL ORAL ANTIPSYCHOTICS
Adverse events: Specific ‐ prolactin‐related ‐ long term It is unclear how adverse events were reported · patients with schizophrenia
It is very uncertain whether RISPERIDONE DEPOT changes adverse events: Specific ‐ prolactin‐related ‐ long term It is… compared with GENERAL ORAL ANTIPSYCHOTICS (very low certainty).
Risperidone (depot) for schizophrenia (2016) · Cochrane Headline outcomes only
RR 10.27 [0.59, 180.05]1 study · 85 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Risperidone (depot) for schizophrenia
2016 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.