Question · asked by 1 review

Bisphosphonates vs placebo/no treatment: Proportion of participants with pain response

Bisphosphonates showed no clear difference in proportion of participants with pain response compared with placebo/no treatment (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Bisphosphonates vs placebo/no treatment
Proportion of participants with pain response · men with advanced prostate cancer
Bisphosphonates showed no clear difference in proportion of participants with pain response compared with placebo/no treatment (low certainty).
Bisphosphonates for advanced prostate cancer (2017) · Cochrane Headline outcomes only
RR 1.15 [0.93, 1.43]3 studies · 876 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Bisphosphonates for advanced prostate cancer
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.