Question · asked by 1 review
Ketamine vs A different sedative agent: Behaviour
- Population
- Children and adolescents (0 to 16 years) needing dental treatment
- Intervention
- Ketamine
- Comparison
- A different sedative agent
- Outcome
- Behaviour
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 3 · 75%Very low 1 · 25%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Ketamine vs A different sedative agent Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2018) · Cochrane All outcomes | Any behavioural score - Ketamine versus (other sedatives): 494 (8); VERY LOW | 8 studies · 494 participants | Very low |
Ketamine vs A different sedative agent Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2012) · Cochrane All outcomesearlier version CD003877.PUB4, superseded | Seven studies evaluated ketamine head-to-head (Abrams 1993; Alfonzo-Echeverri 1993; Bui 2002; Rai 2007; Roelofse 1996a; Roelofse 1996b; Roelofse 1998); results mixed; Rai 2007 higher behaviour scores for ketamine vs… | 7 studies | GRADE not reported |
Ketamine vs A different sedative agent Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2006) · Cochrane All outcomesearlier version CD003877.PUB3, superseded | Ketamine head-to-head (Abrams 1993; Alfonzo-Ech. 1993; Bui 2002; Roelofse 1996b; Roelofse 1998): mixed; ketamine favoured on some overall-evaluation outcomes. Narrative. | Not reported | GRADE not reported |
Ketamine vs A different sedative agent Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2005) · Cochrane All outcomesearlier version CD003877.PUB2, superseded | Ketamine head-to-head: Abrams 1993 (vs midazolam/sufentanil); Alfonzo-Ech. 1993 (vs meperidine/promethazine, no behaviour difference); Bui 2002 (ketamine vs ketamine/promethazine, favoured ketamine); Roelofse… | Not reported | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Sedation of children undergoing dental treatment 2018 · Cochrane All outcomes | 22 February 2018 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.