Question · asked by 1 review
38% silver diamine fluoride vs placebo: Root carious lesions prevention
- Population
- Older adults with root carious lesions (exposed root surfaces)
- Intervention
- 38% silver diamine fluoride
- Comparison
- placebo
- Outcome
- Root carious lesions prevention
38% silver diamine fluoride reduced root-caries increment (DMFRS/DFRS) versus placebo, MD −0.33 (95% CI −0.39 to −0.28) (ungraded).
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
38% silver diamine fluoride vs Placebo Root carious lesions prevention · Older adults with root carious lesions (exposed root surfaces) 38% silver diamine fluoride reduced root-caries increment (DMFRS/DFRS) versus placebo, MD −0.33 (95% CI −0.39 to −0.28) (ungraded). Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) All outcomes | MD -0.33 [-0.39, -0.28] | 2 studies | GRADE not reported |
38% silver diamine fluoride vs Placebo Root carious lesions prevention · Older adults with root carious lesions (exposed root surfaces) 38% silver diamine fluoride had a 72% higher root-caries prevention success rate than placebo (one high-risk-of-bias review, one study; ungraded). Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) All outcomes | Relative success-rate difference (% higher, SDF vs placebo) 72 | 1 study | GRADE not reported |
38% silver diamine fluoride vs Placebo Root carious lesions prevention · Older adults with root carious lesions (exposed root surfaces) Reported prevented fractions for 38% SDF versus placebo for root-caries prevention ranged 25 to 71% across two reviews (four studies; ungraded). Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) All outcomes | Prevented Fraction 25–71 | 4 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Silver diamine fluoride for managing carious lesions: an umbrella review. 2019 All outcomes | June 2018 | 15 | Not applicable |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.