Direct‐acting antivirals vs control: Proportion of participants with no sustained virological response at maximum
It is very uncertain whether direct‐acting antivirals changes proportion of participants with no sustained virological response at… compared with control (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Direct‐acting antivirals vs control Proportion of participants with no sustained virological response at maximum · adults with chronic hepatitis C It is very uncertain whether direct‐acting antivirals changes proportion of participants with no sustained virological response at… compared with control (very low certainty). Direct‐acting antivirals for chronic hepatitis C (2017) · Cochrane Headline outcomes onlyearlier version CD012143.PUB2, superseded | RR 0.44 [0.37, 0.52] | 32 studies · 6886 participants | Very low |
Direct‐acting antivirals vs control Proportion of participants with no sustained virological response at maximum · adults with chronic hepatitis C Direct‐acting antivirals may leads to lower proportion of participants with no sustained virological response at… compared with control (low certainty). Direct‐acting antivirals for chronic hepatitis C (2017) · Cochrane Headline outcomes only | RR 0.44 [0.37, 0.52] | 32 studies · 6886 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Direct‐acting antivirals for chronic hepatitis C 2017 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.