Question · asked by 1 review
Naltrexone/bupropion vs placebo: Change in systolic blood pressure as compared to placebo [mm Hg] from baseline to end of study
- Population
- Men and non‐pregnant women ≥ 18 years old with essential hypertension
- Intervention
- Naltrexone/bupropion
- Comparison
- placebo
- Outcome
- Change in systolic blood pressure as compared to placebo [mm Hg] from baseline to end of study
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Naltrexone/bupropion vs placebo Change in systolic blood pressure as compared to placebo (mm Hg) from baseline to end of study · Men and non‐pregnant women ≥ 18 years old with essential hypertension Long‐term effects of weight‐reducing drugs in people with hypertension (2021) · Cochrane Headline outcomes only | no estimate extracted | 1 study · 8283 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Long‐term effects of weight‐reducing drugs in people with hypertension 2021 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.