Microinvasive techniques (resin infiltration, resin/GIC sealant, or glass ionomer varnish) vs Non-invasive measures (fluoride varnish/toothpaste, flossing, oral hygiene instruction, sham/standard of care): Radiographic proximal caries lesion progression
- Population
- Children and adults with non-cavitated proximal (interproximal) caries lesions in primary and/or permanent teeth (ages 3-45)
- Intervention
- Microinvasive techniques (resin infiltration, resin/GIC sealant, or glass ionomer varnish)
- Comparison
- Non-invasive measures (fluoride varnish/toothpaste, flossing, oral hygiene instruction, sham/standard of care)
- Outcome
- Radiographic proximal caries lesion progression
Microinvasive techniques probably reduce radiographic progression of non-cavitated proximal caries lesions compared with non-invasive measures (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Microinvasive techniques (resin infiltration, resin/GIC sealant, or glass ionomer varnish) vs Non-invasive measures (fluoride varnish/toothpaste, flossing, oral hygiene instruction, sham/standard of care) Radiographic progression of proximal caries lesions · Children and adults with non-cavitated proximal (interproximal) caries lesions in primary and/or permanent teeth (ages… · Final follow-up (1 to 7 years across trials), Multiple countries (Brazil, Saudi Arabia, Netherlands, USA, Turkey, Switzerland, Germany, New Zealand, Chile, Thailand); dental clinic/community settings, Overall (all microinvasive vs non-invasive pooled) Microinvasive techniques probably reduce radiographic progression of non-cavitated proximal caries lesions compared with non-invasive measures (moderate certainty). Microinvasive interventions in the management of proximal caries lesions in primary and permanent teeth-… (2025) All outcomes | OR 0.27 [0.19, 0.38] | 13 studies · 623 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Microinvasive interventions in the management of proximal caries lesions in primary and permanent teeth- systematic review and… 2025 All outcomes | May 2024 | 17 | Low / Critically Low |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Microinvasive techniques (resin infiltration, resin/GIC sealant, or glass ionomer varnish) vs Conventional restoration · Children and adults with non-cavitated proximal (interproximal) caries lesions in… · 1 review
Studies behind the findings
The primary studies the full-text reviews tie to this outcome. Reviews with headline outcomes only do not list them here.
- Arsalan 2020 · included by 1 of these review
- Arslan 2020 · included by 1 of these review
- Arthur 2018 · included by 1 of these review
- Bagher 2018 · included by 1 of these review
- Basili 2017 · included by 1 of these review
- Cristian 2017 · included by 1 of these review
- Foster 2017 · included by 1 of these review
- Jorge 2019 · included by 1 of these review
- Khan 2023 · included by 1 of these review
- Mathilde 2018 · included by 1 of these review
- Meyer 2016 · included by 1 of these review
- Meyer-Lueckel et al. 2016 · included by 1 of these review
- Paris 2020 · included by 1 of these review
- Peters 2018 · included by 1 of these review
- Peters 2019 · included by 1 of these review
- Sarti 2020 · included by 1 of these review
- Treeratweerapong 2023 · included by 1 of these review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.