Question · asked by 1 review

Summary of findings: Inhaled antibiotics plus IV antibiotics vs IV antibiotics: Quality of life: number of participants achieving MCID

Summary of findings: Inhaled antibiotics plus IV antibiotics showed no clear difference in quality of life: number of participants achieving MCID compared with IV antibiotics only (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Summary of findings: Inhaled antibiotics plus IV antibiotics vs IV antibiotics only
Quality of life: number of participants achieving MCID · children and adults with pulmonary exacerbation in CF
Summary of findings: Inhaled antibiotics plus IV antibiotics showed no clear difference in quality of life: number of participants achieving MCID compared with IV antibiotics only (low certainty).
Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis (2022) · Cochrane Headline outcomes only
RR 1.2 [0.61, 2.34]1 study · 16 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis
2022 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.