Question · asked by 1 review

Micro-invasive treatment (proximal sealing or resin infiltration): resin sealant, glass ionomer sealant, polyurethane/adhesive patch, or resin infiltration vs Non-invasive / control treatment: Caries (lesion) progression (radiographic)

Population
Dentate children and adults with non-cavitated proximal caries lesions extending into enamel or dentine (not pulp) in primary or permanent teeth (trial ages 4 to 39 years)
Intervention
Micro-invasive treatment (proximal sealing or resin infiltration): resin sealant, glass ionomer sealant, polyurethane/adhesive patch, or resin infiltration
Comparison
Non-invasive / control treatment
Outcome
Caries (lesion) progression (radiographic)

Micro-invasive treatment (proximal sealing or resin infiltration):… probably leads to lower caries (lesion) progression measured by pairwise reading of… compared with non-invasive measures (e.g. fluoride varnish, flossing/oral hygiene… (moderate certainty).

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 4 · 100%High 0 · 0%
FindingEffectStudiesGRADE certainty
Micro-invasive treatment (proximal sealing or resin infiltration): resin sealant, glass ionomer sealant, polyurethane/adhesive patch, or resin infiltration vs Non-invasive measures (e.g. fluoride varnish, flossing/oral hygiene advice), no treatment, or placebo
Caries (lesion) progression measured by pairwise reading of radiographs · Dentate children and adults with non-cavitated proximal caries lesions extending into enamel or dentine (not pulp) in… · 18 to 36 months (radiographic follow-up)
Micro-invasive treatment (proximal sealing or resin infiltration):… probably leads to lower caries (lesion) progression measured by pairwise reading of… compared with non-invasive measures (e.g. fluoride varnish, flossing/oral hygiene… (moderate certainty).
Micro‐invasive interventions for managing proximal dental decay in primary and permanent teeth (2015) · Cochrane All outcomes
OR 0.31 [0.18, 0.53]4 studiesModerate
Micro-invasive treatment (proximal sealing or resin infiltration): resin sealant, glass ionomer sealant, polyurethane/adhesive patch, or resin infiltration vs Non-invasive measures (e.g. fluoride varnish, flossing/oral hygiene advice), no treatment, or placebo
Caries (lesion) progression (radiographic; most sensitive measure per study, DSR > pairwise > visual scoring) · Dentate children and adults with non-cavitated proximal caries lesions extending into enamel or dentine (not pulp) in… · 12 to 36 months (radiographic follow-up)
Micro-invasive treatment (proximal sealing or resin infiltration):… probably leads to lower caries (lesion) progression (radiographic; most sensitive measure… compared with non-invasive measures (e.g. fluoride varnish, flossing/oral hygiene… (moderate certainty).
Micro‐invasive interventions for managing proximal dental decay in primary and permanent teeth (2015) · Cochrane All outcomes
OR 0.24 [0.14, 0.41]7 studies · 365 participantsModerate
Micro-invasive treatment (proximal sealing or resin infiltration): resin sealant, glass ionomer sealant, polyurethane/adhesive patch, or resin infiltration vs Non-invasive measures (e.g. fluoride varnish, flossing/oral hygiene advice), no treatment, or placebo
Caries (lesion) progression measured by digital subtraction radiography (DSR) · Dentate children and adults with non-cavitated proximal caries lesions extending into enamel or dentine (not pulp) in… · 12 to 18 months (radiographic follow-up)
Micro-invasive treatment (proximal sealing or resin infiltration):… probably leads to lower caries (lesion) progression measured by digital subtraction… compared with non-invasive measures (e.g. fluoride varnish, flossing/oral hygiene… (moderate certainty).
Micro‐invasive interventions for managing proximal dental decay in primary and permanent teeth (2015) · Cochrane All outcomes
OR 0.18 [0.06, 0.50]3 studiesModerate
Micro-invasive treatment (proximal sealing or resin infiltration): resin sealant, glass ionomer sealant, polyurethane/adhesive patch, or resin infiltration vs Non-invasive measures (e.g. fluoride varnish, flossing/oral hygiene advice), no treatment, or placebo
Caries (lesion) progression measured by radiographic scoring · Dentate children and adults with non-cavitated proximal caries lesions extending into enamel or dentine (not pulp) in… · 12 to 30 months (radiographic follow-up)
Micro-invasive treatment (proximal sealing or resin infiltration):… probably leads to lower caries (lesion) progression measured by radiographic scoring compared with non-invasive measures (e.g. fluoride varnish, flossing/oral hygiene… (moderate certainty).
Micro‐invasive interventions for managing proximal dental decay in primary and permanent teeth (2015) · Cochrane All outcomes
OR 0.27 [0.17, 0.44]5 studiesModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Micro‐invasive interventions for managing proximal dental decay in primary and permanent teeth
2015 · Cochrane All outcomes
2014-12-31Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.