Methylphenidate vs placebo or no intervention: QoL
It is very uncertain whether methylphenidate changes quality of life (parent‐rated) compared with placebo or no intervention (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Methylphenidate vs placebo or no intervention Quality of life (parent‐rated) · children and adolescents (up to and including 18 years of age) with ADHD It is very uncertain whether methylphenidate changes quality of life (parent‐rated) compared with placebo or no intervention (very low certainty). Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD) (2023) · Cochrane Headline outcomes only | SMD 0.4 | 4 studies · 608 participants | Very low |
Methylphenidate vs placebo or no intervention Quality of life (Parent‐rated) · children and adolescents (up to and including 18 years of age) with ADHD It is very uncertain whether methylphenidate changes quality of life (Parent‐rated) compared with placebo or no intervention (very low certainty). Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD) (2015) · Cochrane Headline outcomes onlyearlier version CD009885.PUB2, superseded | SMD 0.61 [0.42, 0.8] | 3 studies · 514 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD) 2023 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.