Question · asked by 1 review

SDF applied once (single application, no re-application) vs Other non/minimally-invasive treatment (ART or silver-fluoride varnish): Caries arrest

Population
Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars
Intervention
SDF applied once (single application, no re-application)
Comparison
Other non/minimally-invasive treatment (ART or silver-fluoride varnish)
Outcome
Caries arrest

A single (one-time) SDF application did not significantly arrest caries (pooled ES -0.09, 95% CI -0.48 to 0.29; ungraded).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
SDF applied once (single application, no re-application) vs Other non/minimally-invasive treatment (ART or silver-fluoride varnish)
Caries arrest · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars · Follow-up up to 12 months (single application), Pediatric dental care in hospital, community/school and outpatient settings (Saudi Arabia, China, India, Brazil, Spain), SDF application frequency: single (one-time) application
A single (one-time) SDF application did not significantly arrest caries (pooled ES -0.09, 95% CI -0.48 to 0.29; ungraded).
Silver Diamine Fluoride (SDF) Efficacy in Arresting Cavitated Caries Lesions in Primary Molars: A Systematic… (2022) All outcomes
ES -0.09 [-0.48, 0.29]2 studies · 117 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Silver Diamine Fluoride (SDF) Efficacy in Arresting Cavitated Caries Lesions in Primary Molars: A Systematic Review and Metanalysis.
2022 All outcomes
10 January 2022 (databases searched from inception to 10 January 2022)16Critically Low / Critically Low
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.