Azithromycin vs amoxicillin: Clinical cure
- Population
- group A streptococcal pharyngitis
- Intervention
- Azithromycin
- Comparison
- amoxicillin
- Outcome
- Clinical cure
It is very uncertain whether azithromycin changes clinical cure (ITT analysis) compared with amoxicillin (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Azithromycin vs amoxicillin Clinical cure (ITT analysis) · group A streptococcal pharyngitis It is very uncertain whether azithromycin changes clinical cure (ITT analysis) compared with amoxicillin (very low certainty). Different antibiotic treatments for group A streptococcal pharyngitis (2023) · Cochrane Headline outcomes only | OR 0.76 [0.55, 1.05] | 1 study · 673 participants | Very low |
Azithromycin vs amoxicillin Clinical cure (ITT analysis) · group A streptococcal pharyngitis It is very uncertain whether azithromycin changes clinical cure (ITT analysis) compared with amoxicillin (very low certainty). Different antibiotic treatments for group A streptococcal pharyngitis (2021) · Cochrane Headline outcomes onlyearlier version CD004406.PUB5, superseded | OR 0.76 [0.55, 1.05] | 1 study · 673 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.