Superoxide dismutase (SOD) vs no intervention: Acute and late GI toxicity (grade 2+)
Summary of findings: Superoxide dismutase may leads to lower acute and late GI toxicity (grade 2+) compared with no intervention (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings: Superoxide dismutase vs no intervention Acute and late GI toxicity (grade 2+) · People with rectal cancer Summary of findings: Superoxide dismutase may leads to lower acute and late GI toxicity (grade 2+) compared with no intervention (low certainty). Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary… (2018) · Cochrane Headline outcomes only | RR 0.2 [0.05, 0.86] | 1 study · 92 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic cancers 2018 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.