Question · asked by 1 review

Buspirone vs placebo: Leaving the study early

Population
psychiatric patients (schizophrenia) with antipsychotic‐induced tardive dyskinesia
Intervention
Buspirone
Comparison
placebo
Outcome
Leaving the study early

It is very uncertain whether ANXIOLYTIC ‐ BUSPIRONE changes acceptability of treatment (measured by participants leaving the… compared with PLACEBO (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
ANXIOLYTIC ‐ BUSPIRONE vs PLACEBO
Acceptability of treatment (measured by participants leaving the study early) · female and male 33‐year old (mean) patients with schizophrenia and antipsychotic‐induced tardive dyskinesia
It is very uncertain whether ANXIOLYTIC ‐ BUSPIRONE changes acceptability of treatment (measured by participants leaving the… compared with PLACEBO (very low certainty).
Miscellaneous treatments for antipsychotic‐induced tardive dyskinesia (2018) · Cochrane Headline outcomes only
no estimate extracted1 study · 42 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Miscellaneous treatments for antipsychotic‐induced tardive dyskinesia
2018 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.