Question · asked by 1 review

Children with dental caries vs Children without dental caries: Mean corpuscular volume (MCV)

Population
Children or adolescents
Intervention
Children with dental caries
Comparison
Children without dental caries
Outcome
Mean corpuscular volume (MCV)

MCV tends to be lower in children with dental caries, but the pooled difference is not statistically significant (MD -1.96 fL, 95% CI -4.02 to 0.10; very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Children with dental caries vs Children without dental caries (caries-free)
Mean corpuscular volume (MCV) · Children and adolescents (0-18 years; most included reviews focused on <6 years) · Pediatric populations (community and clinical); various countries (e.g., India, Iran, China, Peru)
MCV tends to be lower in children with dental caries, but the pooled difference is not statistically significant (MD -1.96 fL, 95% CI -4.02 to 0.10; very low certainty).
Association Between Iron Deficiency Anemia and Dental Caries in Children: A Systematic Umbrella Meta-Analysis. (2025) All outcomes
MD -1.96 [-4.02, 0.10]3 studiesVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Association Between Iron Deficiency Anemia and Dental Caries in Children: A Systematic Umbrella Meta-Analysis.
2025 All outcomes
Before January 202513Not applicable
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.