Fluconazole (absorbed from GI tract) vs Ketoconazole (absorbed from GI tract): Mycological: eradication of oral candidiasis
- Population
- Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
- Intervention
- Fluconazole (absorbed from GI tract)
- Comparison
- Ketoconazole (absorbed from GI tract)
- Outcome
- Mycological: eradication of oral candidiasis
Fluconazole (absorbed from GI tract) showed no clear difference in mycological: eradication of oral candidiasis compared with ketoconazole (absorbed from GI tract); GRADE not reported.
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Fluconazole (absorbed from GI tract) vs Ketoconazole (absorbed from GI tract) Mycological: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis Fluconazole (absorbed from GI tract) showed no clear difference in mycological: eradication of oral candidiasis compared with ketoconazole (absorbed from GI tract); GRADE not reported. Interventions for treating oral candidiasis for patients with cancer receiving treatment (2010) · Cochrane All outcomes | RR 0.95 [0.52, 1.72] | 1 study · 37 participants | GRADE not reported |
Fluconazole (absorbed from GI tract) vs Ketoconazole (absorbed from GI tract) Mycological: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis Fluconazole (absorbed from GI tract) showed no clear difference in mycological: eradication of oral candidiasis compared with ketoconazole (absorbed from GI tract); GRADE not reported. Interventions for treating oral candidiasis for patients with cancer receiving treatment (2007) · Cochrane All outcomesearlier version CD001972.PUB3, superseded | RR 0.95 [0.52, 1.72] | 1 study · 37 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for treating oral candidiasis for patients with cancer receiving treatment 2010 · Cochrane All outcomes | 2010-06 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Fluconazole (absorbed from GI tract) vs Itraconazole · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral… · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.