Question · asked by 1 review

Pregabalin 600 mg vs placebo: Participant‐reported pain relief of 50% or greater

Population
adults with moderate or severe pain associated with painful diabetic neuropathy
Intervention
Pregabalin 600 mg
Comparison
placebo
Outcome
Participant‐reported pain relief of 50% or greater

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Pregabalin 600 mg vs placebo
At least 50% pain intensity reduction · adults with moderate or severe pain associated with painful diabetic neuropathy
Pregabalin for neuropathic pain in adults (2019) · Cochrane Headline outcomes only
no estimate extracted7 studies · 1360 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pregabalin for neuropathic pain in adults
2019 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.