Question · asked by 1 review

Intravenous ketorolac vs NSAIDs: Participant‐reported pain relief of 50% or greater

Intravenous ketorolac showed no clear difference in number of participants with at least 50% pain relief over 4 hours compared with another NSAID (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Intravenous ketorolac vs another NSAID
Number of participants with at least 50% pain relief over 4 hours · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic…
Intravenous ketorolac showed no clear difference in number of participants with at least 50% pain relief over 4 hours compared with another NSAID (low certainty).
Single‐dose intravenous ketorolac for acute postoperative pain in adults (2021) · Cochrane Headline outcomes only
RR 1.04 [0.89, 1.21]4 studies · 337 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Single‐dose intravenous ketorolac for acute postoperative pain in adults
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.