Question · asked by 1 review

1055 to 1100 ppm F toothpaste vs 500 to 550 ppm F toothpaste: Adverse effects of toothpaste

Population
Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
Intervention
1055 to 1100 ppm F toothpaste
Comparison
500 to 550 ppm F toothpaste
Outcome
Adverse effects of toothpaste

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
1055 to 1100 ppm F toothpaste vs 500 to 550 ppm F toothpaste
Adverse effects of toothpaste · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start) · 12 months
Fluoride toothpastes of different concentrations for preventing dental caries (2019) · Cochrane All outcomes
Adverse effects of toothpaste: not estimable. "There were no reports on adverse effects, but some children complained about the taste of the dentifrice" (Cardoso 2014); 195 participants (1 RCT); low-certainty.1 study · 195 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Fluoride toothpastes of different concentrations for preventing dental caries
2019 · Cochrane All outcomes
2018-08Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.