Question · asked by 1 review

Laser fluorescence (LF; DIAGNOdent) vs Reference standard (histology, excavation, or enhanced visual examination): Relative DOR by setting (LF, advanced, occlusal permanent)

Population
Permanent teeth, occlusal surfaces, with suspected caries lesions
Intervention
Laser fluorescence (LF; DIAGNOdent)
Comparison
Reference standard (histology, excavation, or enhanced visual examination)
Outcome
Relative DOR by setting (LF, advanced, occlusal permanent)

For LF on occlusal permanent teeth (advanced threshold), laboratory studies had significantly lower diagnostic accuracy than clinical studies (RDOR 0.28, 0.12 to 0.66).

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Laser fluorescence (LF; DIAGNOdent) vs Reference standard (histological examination, operative intervention, or other/visual examination)
Relative DOR by setting (LF, advanced, occlusal permanent) · Permanent teeth, occlusal surfaces, with suspected caries lesions · More advanced (dentine/cavitated) caries lesions threshold, Meta-regression across clinical and laboratory studies, Laboratory vs clinical (reference)
For LF on occlusal permanent teeth (advanced threshold), laboratory studies had significantly lower diagnostic accuracy than clinical studies (RDOR 0.28, 0.12 to 0.66).
Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of… (2013) All outcomes
RDOR 0.28 [0.12, 0.66]Not reportedGRADE not reported
Laser fluorescence (LF; DIAGNOdent) vs Reference standard (histological examination, operative intervention, or other/visual examination)
Relative DOR by setting (LF, advanced, occlusal permanent) · Permanent teeth, occlusal surfaces, with suspected caries lesions · More advanced (dentine/cavitated) caries lesions threshold, Meta-regression across clinical and laboratory studies, Laboratory using frozen teeth vs clinical (reference)
No significant difference between laboratory-frozen and clinical LF studies (RDOR 0.45, 0.12 to 1.67).
Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of… (2013) All outcomes
RDOR 0.45 [0.12, 1.67]Not reportedGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of heterogeneity.
2013 All outcomes
19 June 201275Not applicable
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.