Question · asked by 1 review

Brush biopsy (oral cytology) vs Surgical or punch biopsy with histological assessment: Sensitivity

Population
Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous oral lesions
Intervention
Brush biopsy (oral cytology)
Comparison
Surgical or punch biopsy with histological assessment
Outcome
Sensitivity

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Oral cytology (e.g. brush cytology, OralCDx brush biopsy) vs Surgical or punch biopsy with histological assessment
Sensitivity · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous…
Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically… (2021) · Cochrane All outcomes
Sensitivity 0.90 [0.82, 0.94]20 studiesModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions
2021 · Cochrane All outcomes
2020-10-20Not listedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.