Question · asked by 1 review

Oral antibiotics vs IV antibiotics: FEV1 % predicted: absolute change from baseline

Population
adults and children with cystic fibrosis (during acute exacerbations of lung disease)
Intervention
Oral antibiotics
Comparison
IV antibiotics
Outcome
FEV1 % predicted: absolute change from baseline

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Oral antibiotics vs IV antibiotics
FEV1 (% predicted) absolute change · people with cystic fibrosis experiencing a pulmonary exacerbation
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis (2015) · Cochrane Headline outcomes only
no estimate extracted1 study · 24 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis
2015 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.