Question · asked by 1 review

Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo: Interferon + SSA (2 RCTs; 171 participants)

It is very uncertain whether estimates of effects, ranking, and certainty of evidence for… changes interferon + SSA (2 RCTs; 468 participants) compared with placebo (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo
Interferon + SSA (2 RCTs; 468 participants)
It is very uncertain whether estimates of effects, ranking, and certainty of evidence for… changes interferon + SSA (2 RCTs; 468 participants) compared with placebo (very low certainty).
Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta‐analysis (2021) · Cochrane Headline outcomes only
HR 0.34 [0.14, 0.8]2 studies · 468 participantsVery low
Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo
Interferon + SSA (4 RCTs; 283 participants)
It is very uncertain whether estimates of effects, ranking, and certainty of evidence for… changes interferon + SSA (4 RCTs; 283 participants) compared with placebo (very low certainty).
Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta‐analysis (2021) · Cochrane Headline outcomes only
OR 5.71 [1.9, 17.2]4 studies · 283 participantsVery low
Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo
Interferon + SSA (3 RCTs; 512 participants)
It is very uncertain whether estimates of effects, ranking, and certainty of evidence for… changes interferon + SSA (3 RCTs; 512 participants) compared with placebo (very low certainty).
Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta‐analysis (2021) · Cochrane Headline outcomes only
HR 0.23 [0.06, 0.93]3 studies · 512 participantsVery low
Estimates of effects, ranking, and certainty of evidence for different treatment options vs placebo
Interferon + SSA (2 RCTs; 171 participants)
It is very uncertain whether estimates of effects, ranking, and certainty of evidence for… changes interferon + SSA (2 RCTs; 171 participants) compared with placebo (very low certainty).
Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta‐analysis (2021) · Cochrane Headline outcomes only
OR 2.88 [1.16, 7.13]2 studies · 171 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta‐analysis
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.