Question · asked by 1 review

Norfloxacin plus amphotericin B vs Amphotericin B: Oral candidiasis (present)

Population
Patients with cancer receiving chemotherapy and/or radiotherapy
Intervention
Norfloxacin plus amphotericin B
Comparison
Amphotericin B
Outcome
Oral candidiasis (present)

Norfloxacin plus amphotericin B showed no clear difference in oral candidiasis (present) compared with amphotericin B; GRADE not reported.

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Norfloxacin plus amphotericin B vs Amphotericin B
Oral candidiasis (present) · Patients with cancer receiving chemotherapy or radiotherapy or both
Norfloxacin plus amphotericin B showed no clear difference in oral candidiasis (present) compared with amphotericin B; GRADE not reported.
Interventions for preventing oral candidiasis for patients with cancer receiving treatment (2007) · Cochrane All outcomes
RR 0.38 [0.15, 1.0]1 study · 106 participantsGRADE not reported
Norfloxacin plus amphotericin B vs Amphotericin B
Oral candidiasis (present) · Patients with cancer receiving chemotherapy and/or radiotherapy
Norfloxacin plus amphotericin B showed no clear difference in oral candidiasis (present) compared with amphotericin B; GRADE not reported.
Interventions for preventing oral candidiasis for patients with cancer receiving treatment (2004) · Cochrane All outcomesearlier version CD003807.PUB2, superseded
RR 0.38 [0.15, 1.0]1 study · 106 participantsGRADE not reported
Norfloxacin plus amphotericin B vs Amphotericin B
Oral candidiasis (present) · Patients with cancer receiving chemotherapy and/or radiotherapy
Norfloxacin plus amphotericin B showed no clear difference in oral candidiasis (present) compared with amphotericin B; GRADE not reported.
Interventions for preventing oral candidiasis for patients with cancer receiving treatment (2002) · Cochrane All outcomesearlier version CD003807, superseded
RR 0.38 [0.15, 1.0]1 study · 106 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for preventing oral candidiasis for patients with cancer receiving treatment
2007 · Cochrane All outcomes
2009-08Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.