Question · asked by 1 review

Anti‐VEGF vs sham: QoL

Population
macular oedema secondary to branch retinal vein occlusion
Intervention
Anti‐VEGF
Comparison
sham
Outcome
QoL

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Anti‐VEGF vs sham
Mean change in quality of life (QoL) at 12 months on the National Eye Institute Visual Functioning Questionnaire‐25 (VFQ‐25) (scored 0 to 100) (higher score is better quality of life) · macular oedema secondary to branch retinal vein occlusion
Anti‐vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion (2020) · Cochrane Headline outcomes only
no estimate extracted1 study · 281 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Anti‐vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.