Question · asked by 1 review

HALOPERIDOL vs first‐generation antipsychotics: Response to treatment (medium term) Clinically important response to treatment as defined by each study

Haloperidol may leads to lower clinically important response to treatment (medium term) compared with first‐generation antipsychotics (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Haloperidol vs first‐generation antipsychotics
Clinically important response to treatment (medium term) · people with schizophrenia
Haloperidol may leads to lower clinically important response to treatment (medium term) compared with first‐generation antipsychotics (low certainty).
Haloperidol versus first‐generation antipsychotics for the treatment of schizophrenia and other psychotic… (2015) · Cochrane Headline outcomes only
RR 0.51 [0.37, 0.69]1 study · 80 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Haloperidol versus first‐generation antipsychotics for the treatment of schizophrenia and other psychotic disorders
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.