Question · asked by 1 review

High vs low or no hyaluronic acid: Live birth rate

High probably leads to higher live birth rate ‐ high vs low or no hyaluronic acid compared with low or no hyaluronic acid (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
High vs low or no hyaluronic acid
Live birth rate ‐ high vs low or no hyaluronic acid · couples undergoing embryo transfer
High probably leads to higher live birth rate ‐ high vs low or no hyaluronic acid compared with low or no hyaluronic acid (moderate certainty).
Hyaluronic acid in embryo transfer media for assisted reproductive technologies (2020) · Cochrane Headline outcomes only
RR 1.21 [1.11, 1.31]10 studies · 4066 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Hyaluronic acid in embryo transfer media for assisted reproductive technologies
2020 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.