Question · asked by 1 review
Antifungal drugs partially absorbed from GI tract (miconazole, clotrimazole) vs placebo or no treatment: Toxicity (adverse events probably due to drug)
- Population
- Patients with cancer receiving chemotherapy and/or radiotherapy
- Intervention
- Antifungal drugs partially absorbed from GI tract (miconazole, clotrimazole)
- Comparison
- placebo or no treatment
- Outcome
- Toxicity (adverse events probably due to drug)
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Antifungal drugs partially absorbed from GI tract (miconazole, clotrimazole) vs Placebo or no treatment Toxicity (adverse events probably due to drug) · Patients with cancer receiving chemotherapy or radiotherapy or both Interventions for preventing oral candidiasis for patients with cancer receiving treatment (2007) · Cochrane All outcomes | 2 studies, 60 participants; effect not estimable (no events reported) | 2 studies · 60 participants | GRADE not reported |
Antifungal drugs partially absorbed from GI tract (miconazole, clotrimazole) vs Placebo or no treatment Toxicity (adverse events probably due to drug) · Patients with cancer receiving chemotherapy and/or radiotherapy Interventions for preventing oral candidiasis for patients with cancer receiving treatment (2004) · Cochrane All outcomesearlier version CD003807.PUB2, superseded | 2 studies, 60 participants; effect not estimable (no events reported) | 2 studies · 60 participants | GRADE not reported |
Antifungal drugs partially absorbed from GI tract (miconazole, clotrimazole) vs Placebo or no treatment Toxicity (adverse events probably due to drug) · Patients with cancer receiving chemotherapy and/or radiotherapy Interventions for preventing oral candidiasis for patients with cancer receiving treatment (2002) · Cochrane All outcomesearlier version CD003807, superseded | 2 studies, 60 participants; effect not estimable (no events reported) | 2 studies · 60 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes | 2009-08 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.