Clonazepam vs carbamazepine: Proportion of participants with treatment‐emergent adverse events (TEAEs) ‐ Leading to discontinuation during the treatment period № of participants: 36 (1 RCT)
It is very uncertain whether clonazepam changes proportion of participants with treatment‐emergent adverse events… compared with carbamazepine (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Clonazepam vs carbamazepine Proportion of participants with treatment‐emergent adverse events (TEAEs) leading to discontinuation during the treatment period (1 RCT; n = 36) · people with newly diagnosed epilepsy It is very uncertain whether clonazepam changes proportion of participants with treatment‐emergent adverse events… compared with carbamazepine (very low certainty). Clonazepam monotherapy for treating people with newly diagnosed epilepsy (2022) · Cochrane Headline outcomes only | RR 2.61 [0.8, 8.52] | Not reported | Very low |
Clonazepam vs carbamazepine Proportion of participants with treatment‐emergent adverse events (TEAEs) ‐ Leading to discontinuation during the treatment period № of participants: 36 (1 RCT) · people with newly diagnosed epilepsy It is very uncertain whether clonazepam changes proportion of participants with treatment‐emergent adverse events… compared with carbamazepine (very low certainty). Clonazepam monotherapy for treating people with newly diagnosed epilepsy (2019) · Cochrane Headline outcomes onlyearlier version CD013028.PUB2, superseded | RR 2.61 [0.8, 8.52] | Not reported | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Clonazepam monotherapy for treating people with newly diagnosed epilepsy 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.