Question · asked by 1 review
Keratinocyte GF vs placebo: Oral mucositis (severe)
- Population
- Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
- Intervention
- Keratinocyte GF
- Comparison
- placebo
- Outcome
- Oral mucositis (severe)
Keratinocyte GF may leads to lower oral mucositis (severe) compared with placebo (low certainty).
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 1 · 50%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Keratinocyte GF vs Placebo Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies · Median 28 days Keratinocyte GF may leads to lower oral mucositis (severe) compared with placebo (low certainty). Interventions for preventing oral mucositis for patients with cancer receiving treatment (2011) · Cochrane All outcomes | RR 0.72 [0.58, 0.9] | 6 studies · 559 participants | Low |
Keratinocyte GF vs Placebo Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies · Median 28 days Keratinocyte GF led to lower oral mucositis (severe) compared with placebo; GRADE not reported. Interventions for preventing oral mucositis for patients with cancer receiving treatment (2010) · Cochrane All outcomesearlier version CD000978.PUB4, superseded | RR 0.72 [0.58, 0.9] | 6 studies · 559 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for preventing oral mucositis for patients with cancer receiving treatment 2011 · Cochrane All outcomes | 2011-02 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.